US stroke deaths, ages 45–64: 21.7 per 100,000 in 2019, 24.4 in 2021 (+12%)

The chart shows US stroke deaths per 100,000 adults aged 45–64. After falling to 20.2 in 2012 and creeping up to 21.7 in 2019, the rate jumped to 24.0 in 2020, peaked at 24.4 in 2021 (+12% vs 2019) and was still 23.9 in 2022.
Source: Curtin, NCHS Data Brief No. 505, data as of 2002–2022